Alkylated Derivatives of piperazine Compounds, Pharmaceutical composition that comprises； a process for preparing the pharmaceutical composition, Kit and use in the treatment of immune disorders, cancer, cardiovascular disease, inflammation, among others.
Alkylated piperazine compounds of Formula I are provided, including stereoisomers, tautomers, and pharmaceutically acceptable salts thereof, useful for inhibiting Btk kinase, and for treating immune disorders such as inflammation mediated by Btk kinase. Methods of using compounds of Formula I for in vitro, in situ, and in vivo diagnosis, and treatment of such disorders in mammalian cells, or associated pathological conditions, are disclosed.COMPUESTOS DERIVADOS DE PIPERAZINA ALQUILADOS； COMPOSICION FARMACEUTICA QUE LOS COMPRENDE； PROCESO PARA PREPARAR LA COMPOSICION FARMACEUTICA； KIT Y USO EN EL TRATAMIENTO DE TRASTORNOS INMUNES, CANCER, ENFERMEDADES CARDIOVASCULARES, INFLAMACION, ENTRE OTROS.
