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Fused Pyrazole Derivatives, Preparation Method Thereof, And Use Thereof In Treatment Of Cancers, Inflammation And Immune Diseases
专利权人:
BEIJING INNOCARE PHARMA TECH CO.; LTD.
发明人:
CHEN, Xiangyang,PANG, Yucheng
申请号:
SG11201806438U
公开号:
SG11201806438UA
申请日:
2016.12.28
申请国别(地区):
SG
年份:
2018
代理人:
摘要:
The present invention relates to pyrazole fused-ring derivatives, their preparation methods, and use thereof in medicine. In particular, the present invention relates to a novel derivative 5 represented by formula (I), and a pharmaceutically acceptable salt thereof or a pharmaceutical composition comprising the same and a method for preparing the same. The present invention also relates to use of the derivatives and the pharmaceutically acceptable salt thereof or the pharmaceutical composition comprising the same in the preparation of therapeutic agents, in particular Bruton tyrosine kinase inhibitors, and preparing a medicament for treating and/or 10 preventing tumors and inflammatory associated diseases. The substituents on formula (I) are defined same as in the specification. B i- `B- Li ., P -----L , A3 R 4 N, 1 A v A .1 "-A2 - --L2 - - ^ . R2 (I) 15
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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