Pharmaceutical composition for preventing or treating immune diseases or inflammatory diseases comprising mesenchymal stem cells stimulated by inflammation
The present invention relates to a pharmaceutical composition for preventing or treating immune diseases or inflammatory diseases comprising mesenchymal stem cells stimulated by inflammation, and a method for producing mesenchymal stem cells for preventing or treating immune diseases or inflammatory diseases. The inflammation-stimulated mesenchymal stem cell of the present invention has an effect of secreting acetylcholine, can be used as an alternative to existing immunosuppressants and inflammation inhibitors with known side effects, and can be used economically. It can be usefully used for prevention or treatment of immune diseases and inflammatory diseases.本発明は、炎症刺激された間葉系幹細胞を含む免疫疾患または炎症疾患の予防または治療用薬学的組成物、免疫疾患または炎症疾患の予防または治療用間葉系幹細胞の製造方法に関する。本発明の炎症刺激された間葉系幹細胞は、アセチルコリンを分泌する効果があり、副作用が知られた既存の免疫抑制剤及び炎症抑制剤の代わりとなり得、経済的に使用され得る細胞治療剤として免疫疾患及び炎症疾患の予防または治療に有用に利用できる。
