The present invention relates to novel antibodies and antibody fragments that specifically bind to B cell mature antigen (BCMA), particularly full-human single chain antibody scFv. The invention also relates to nucleic acids encoding the antibodies, vectors and host cells expressing the nucleic acids. Furthermore, the invention also relates to compositions comprising the antibodies of the invention, and their use in therapy and diagnosis.本發明涉及特異性結合B細胞成熟抗原(BCMA)的新型抗體和抗體片段,尤其是全人源的單鏈抗體scFv。本發明還涉及編碼這些抗體的核酸、載體和表達該核酸的宿主細胞。此外,本發明也涉及包含本發明抗體的組合物、及其在治療和診斷中的用途。