The present invention relates to novel antibodies and antibody fragments that specifically bind to CD30, especially fully human single-chain antibodies scFvs. The invention also relates to nucleic acids encoding these antibodies, vectors and host cells expressing said nucleic acids. In addition, the present invention also relates to a composition comprising the antibody of the present invention and its uses in therapy and diagnosis.本發明涉及特異性結合CD30的新型抗體和抗體片段,尤其是全人源的單鏈抗體scFv。本發明還涉及編碼這些抗體的核酸、載體和表達該核酸的宿主細胞。此外,本發明也涉及包含本發明抗體的組成物、及其在治療和診斷中的用途。