BRUNO GILBERT MARC ROBERT,DAVID BECHARD,GUY LUC MICHEL DE MARTYNOFF,GÉRALDINE TEPPAZ,SÉBASTIEN DANIEL MORISSEAU,YANNICK LAURENT JOSEPH JACQUES
申请号:
BR112013033350
公开号:
BR112013033350A2
申请日:
2012.06.22
申请国别(地区):
BR
年份:
2017
代理人:
摘要:
The present invention relates to an immunocytokine comprising (a) a conjugate, and (b) an antibody or a fragment thereof directly or indirectly linked by covalence to said conjugate, wherein said conjugate comprises (i) a polypeptide comprising the amino acid sequence of the interleukin 15 or derivatives thereof, and a polypeptide comprising the amino acid sequence of the sushi domain of the IL-15R± or derivatives thereof and uses thereof.