INC.;THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES;THE HENRY M. JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE
发明人:
DALY, MICHAEL J.,GAIDAMAKOVA, ELENA K.,MATROSOVA, VERA K.,LEVINE, RODNEY L.,WEHR, NANCY B.
申请号：
CA2695950
公开号：
CA2695950C
申请日:
2008.08.18
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
This invention encompasses methods of preserving protein function bycontacting aprotein with a composition comprising one or more purine or pyrimidinenucleosides (such ase.g., adenosine or uridine) and an antioxidant (such as e.g., manganese). Inaddition, theinvention encompasses methods of treating and/or preventing a side effect ofradiation exposureand methods of preventing a side effect of radiotherapy comprisingadministration of apharmaceutically effective amount of a composition comprising one or morepurine orpyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant(such as e.g.,manganese) to a subject in need thereof. The compositions may comprise D.radioduransextracts.
