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Compositions Containing Nucleosides and Manganese and Their Uses
专利权人:
The Government of the USA as Represented by the Secretary Department of Health and Human Services;The Henry M. Jackson Foundation for the Advancement of Military Medicine, Inc
发明人:
Michael J. Daly,Elena K. Gaidamakova,Vera Y. Matrosova,Rodney L. Levine,Nancy B. Wehr
申请号:
US16504941
公开号:
US20200188515A1
申请日:
2019.07.08
申请国别(地区):
US
年份:
2020
代理人:
摘要:
This invention encompasses methods of preserving protein function by contacting a protein with a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese). In addition, the invention encompasses methods of treating and/or preventing a side effect of radiation exposure and methods of preventing a side effect of radiotherapy comprising administration of a pharmaceutically effective amount of a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese) to a subject in need thereof. The compositions may comprise D. radiodurans extracts.
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