THE HENRY JACKSON FOUNDATION FOR THE ADVANCEMENT OF MILITARY MEDICINE, INC.;THE GOVERNMENT OF THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES
发明人:
Michael J. Daly,Elena K. Gaidamakova,Vera Y. Matrosova,Rodney L. Levine,Nancy B. Wehr
申请号：
US14920765
公开号：
US10342871B2
申请日:
2015.10.22
申请国别(地区):
US
年份:
2019
代理人:
摘要：
This invention encompasses methods of preserving protein function by contacting a protein with a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese). In addition, the invention encompasses methods of treating and/or preventing a side effect of radiation exposure and methods of preventing a side effect of radiotherapy comprising administration of a pharmaceutically effective amount of a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e g., manganese) to a subject in need thereof. The compositions may comprise D. radiodurans extracts.
