The Henry M Jackson Foundation for the Advancement of Military Medicine, Inc.; as represented by the Secretary;The Government of the United States of America; Department of Health and Human Services;The Government of the United States of America, as represented by the Secretary, Department of Health and Human Services
发明人:
Daly, Michael J.,Gaidamakova, Elena K.,Matrosova, Vera K.,Levine, Rodney L.,Wehr, Nancy B.
申请号:
AU2016222458
公开号:
AU2016222458B2
申请日:
2016.09.01
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
#$%^&*AU2016222458B220181108.pdf#####ABSTRACT This invention encompasses methods of preserving protein function by contacting a 5 protein with a composition comprising one or more purine or pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese). In addition, the invention encompasses methods of treating and/or preventing a side effect of radiation exposure and methods of preventing a side effect of radiotherapy comprising administration of a pharmaceutically effective amount of a composition comprising one or more purine or 10 pyrimidine nucleosides (such as e.g., adenosine or uridine) and an antioxidant (such as e.g., manganese) to a subject in need thereof. The compositions may comprise D. radiodurans extracts.