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5-BIPHENYL-4-HETEROARYLCARBONYLAMINO-PENTANOIC ACID DERIVATIVES AS NEPRILYSIN INHIBITORS
专利权人:
LLC;THERAVANCE BIOPHARMA R&D IP
发明人:
FLEURY, MELISSA,BEAUSOLIEL, ANNE-MARIE,HUGHES, ADAM D.,LONG, DANIEL D.,WILTON, DONNA A.A.
申请号:
SG11201606057P
公开号:
SG11201606057PA
申请日:
2015.01.29
申请国别(地区):
SG
年份:
2016
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula I: where R1, R2a, R2b, and R3-R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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