SUBSTITUTED AMMINOBUTYRIC DERIVATIVES AS NEPRILYSIN INHIBITORS

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专利权人:

THERAVANCE BIOPHARMA R & D IP; LLC

发明人:

FLEURY MELISA,HUGHES ADAM D,GENDRON ROLAND

申请号：

ZA201305826

公开号：

ZA201305826B

申请日:

2013.08.01

申请国别(地区):

ZA

年份:

2014

代理人:

摘要：

In one aspect, the invention relates to compounds having the formula: where R1-R6, a, b, Z, and X are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising such compounds； methods of using such compounds； and processes and intermediates for preparing such compounds.

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中国工程科技知识中心

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