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DERIVES D'ACIDE 5-BIPHENYL-4-HETEOARYLCARBONYLAMINO-PENTANOIQUE UTILISES EN TANT QU'INHIBITEURS DE NEPRILYSINE
专利权人:
LLC;THERAVANCE BIOPHARMA R&D IP
发明人:
FLEURY, MELISSA,BEAUSOLIEL, ANNE-MARIE,HUGHES, ADAM D.,LONG, DANIEL D.,WILTON, DONNA A.A.
申请号:
CA2934898
公开号:
CA2934898A1
申请日:
2015.01.29
申请国别(地区):
CA
年份:
2015
代理人:
摘要:
In one aspect, the invention relates to compounds having the formula (I): where R1, R2a, R2b, and R3-R6 are as defined in the specification, or a pharmaceutically acceptable salt thereof. These compounds have neprilysin inhibition activity. In another aspect, the invention relates to pharmaceutical compositions comprising these compounds; methods of using these compounds; and processes and intermediates for preparing these compounds.
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中国工程科技知识中心
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