For example as for this invention, the difficult water soluble medicine the liquefied medium which the medicine manufacture study is allowed (, being the medicine composition in order to decentralize) solubilization or such as fat emulsion, for example (i) the base (, it is the medicine composition which features that), (ro) the difficult water soluble medicine and (ha) the fatty acid or the salt which such as polyethylene glycol that medicine manufacture study is allowed is contained. With the liquefied medium which the medicine manufacture study is allowed be able to mix this medicine composition, at brief it can mix, for example, the occasion where medicine formulation for dosage such as injection is obtained, at the same time the difficult water soluble medicine to liquefied medium uniformly solubilization or it can decentralize.本発明は、難水溶性薬物を製薬学的に許容される液状媒体(例えば、脂肪乳剤等)に可溶化又は分散化するための医薬組成物であって、(イ)基剤(例えば、ポリエチレングリコール等)、(ロ)難水溶性薬物及び(ハ)脂肪酸又はその製薬学的に許容される塩を含有することを特徴とする医薬組成物である。この医薬組成物は、製薬学的に許容される液状媒体と混和して、例えば、注射液等の投与用医薬製剤を得る際、短時間で混和でき、かつ難水溶性薬物を液状媒体に均一に可溶化又は分散化できる。
