THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO;PETER ST. GEORGE-HYSLOP;JOANNE MCLAURIN
发明人:
PETER ST. GEORGE-HYSLOP,JOANNE MCLAURIN
申请号：
IL19653209
公开号：
IL196532A
申请日:
2009.01.15
申请国别(地区):
IL
年份:
2013
代理人:
摘要：
The present invention relates to immunogenic compositions and peptides comprising residues 4-10 (FRHDSGY) of the amyloid peptide Abeta42. The invention further relates to antibodies that bind to the Abeta(4-10) antigenic determinant. The invention provides methods for treating Alzheimer's disease and for reducing the amyloid load in Alzheimers patients. The invention also relates to methods for designing small molecule inhibitors of amyloid deposition.
