THE GOVERNING COUNCIL OF THE UNIVERSITY OF TORONTO
发明人:
ST. GEORGE-HYSLOP, PETER,MCLAURIN, JOANNE
申请号:
CA2481952
公开号:
CA2481952C
申请日:
2003.04.07
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to immunogenic compositions and peptidescomprising residues 4-10 (FRHDSGY) of the amyloid peptide Abeta42. Theinvention further relates to antibodies that bind to the Abeta(4-10) antigenicdeterminant. The invention provides methods for treating Alzheimer's diseaseand for reducing the amyloid load in Alzheimers patients. The invention alsorelates to methods for designing small molecule inhibitors of amyloiddeposition.