Use of antibodies that specifically bind to amyloid-beta peptide for the manufacture of medicaments for treating diseases characterized by aberrant deposition of amyloid-beta, pharmaceutical compositions comprising them and methods for making them
Monoclonal antibody 9TL and antibodies derived from 9TL directed against amyloid-beta peptide and methods of using same for diagnosing and treatment of Alzheimers disease and Aβ peptide associated diseases are described. Methods of using antibodies directed against amyloid-beta peptide having impaired effector function for treatment of Alzheimers disease and Aβ peptide associated diseases are also described.Linvention porte sur lanticorps monoclonal 9TL et sur des anticorps en dérivant dirigés contre le peptide amyloïde bêta et sur leurs procédés dutilisation pour diagnostiquer et traiter la maladie dAlzheimer et les maladies associées au peptide Aß. Linvention porte également sur des procédés dutilisation danticorps dirigés contre le peptide amyloïde bêta, a fonction effecteur affaiblie, pour traiter la maladie dAlzheimer et les maladies associées au peptide Aß.
