A novel lipid-substance-P conjugate

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专利权人:

发明人:

윤강준,손영숙,홍현숙,임선기,김상민

申请号：

KR1020110089415

公开号：

KR1014374710000B1

申请日:

2011.09.05

申请国别(地区):

KR

年份:

2014

代理人:

摘要：

PURPOSE: A novel lipid-substance-P conjugate is provided to improve stability in vivo and in vitro. CONSTITUTION: A novel lipid-substance-P conjugate contains lipid which is conjugated at one or more sites of amino acid sequence number 1. The lipid is conjugated at an arginine residue at a first site of amino acid sequence number 1. The lipid is C12-C16 fatty acid. The lipid is palmitate.본 발명은 신규한 지질-서브스턴스-P 접합체를 제공한다. 본 발명의 지질-서브스턴스-P 접합체는 시험관내 또는 생체내에서 향상된 안정성을 가지며, 특히, 증가된 생체내 반감기를 나타낸다.

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