NUCLEIC ACID CONSTRUCTS COMPRISING GENE EDITING MULTI-SITES AND USES THEREOF

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专利权人:

IO BIOSCIENCES; INC.

发明人:

Sicco Hans POPMA,Di ZHANG

申请号：

US16486804

公开号：

US20190381192A1

申请日:

2018.02.22

申请国别(地区):

US

年份:

2019

代理人:

摘要：

Disclosed herein is a polynucleotide construct comprising one or more primary endonuclease recognition sequences upstream and downstream of a multiple gene editing site that comprises a plurality of secondary endonuclease recognition sequences. The primary endonuclease recognition sequences facilitate insertion of the multiple gene editing site into a host cell genome. The secondary endonuclease recognition sequences facilitate insertion of one or more exogenous donor genes into the host cell.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/