The invention relates to a secure connector set for a liquid circuit, including: a male connector and a female connector, each including a proximal coupler and a distal coupler, the distal coupler of each connector defining a passage and including a tubular part, in which a connection member fixedly mounted on the proximal coupler extends coaxially, and an elastically deformable membrane which is substantially tubular, closed at a distal end by a membrane body, and movable between a downstream plugging position, in which the membrane sealingly covers a free end of the connection member, and an upstream connection position, in which the connection member passes through the membrane, in which the tubular part of the distal coupler of the male connector is designed to be inserted, upon connection, into the tubular part of the distal coupler of the female connector, and wherein, in a downstream plugging position, for the male and the female connectors, the membrane sealingly blocks the passage in the distal coupler.