Jie Zhang,Kevin S. Warner,Michael A. Ashburn,Larry D. Rigby,Suyi Niu
申请号:
US14533419
公开号:
US20150126481A1
申请日:
2014.11.05
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present disclosure is drawn to an adhesive peel-forming formulation for dermal delivery of a drug, comprising a drug, a solvent vehicle, and a polymer peel-forming agent. The solvent vehicle can comprise a volatile solvent system comprising one or more volatile solvent, and a non-volatile solvent system comprising two or more non-volatile solvents. The non-volatile solvent system can have a solubility with respect to the drug that is within a window of operable solubility such that the drug is deliverable at therapeutically effective rates over a sustained period of time.