The invention relates to the technical field of Chinese herbal preparations, specifically to a preparation method for a wall-broken dendrobium preparation. The preparation method for the wall-broken dendrobium preparation comprises the following steps: crushing dendrobium into wall-broken powder then carrying out ethanol-water wet granulation by controlling the mass of an ethanol solution and the wall-broken powder carrying out extrusion forming at a certain rotating speed and then carrying out drying. The preparation method has a high granulation rate and the prepared wall-broken dendrobium preparation has high bioavailability, good stability and good disintegration performance.本發明涉及一種中藥製劑,具體來說,涉及一種石斛破壁製劑的製備方法。發明通過將石斛粉碎成為破壁粉,通過對乙醇溶液和破壁粉的品質的控制,進行乙醇-水濕法製粒,並在一定的轉速下擠壓成型,乾燥,本方法成粒率高,由此製得的石斛破壁製劑具有較高的生物利用率,並且製劑穩定性強、崩解性好。
