The invention relates to the technical field of Chinese herbal preparations, specifically to a wall-broken giant knotweed rhizome preparation. The wall-broken giant knotweed rhizome preparation is prepared by crushing giant knotweed rhizome into ultrafine powder, then carrying out ethanol-water wet granulation, carrying out extrusion forming at a certain rotating speed and then carrying out drying. The prepared wall-broken giant knotweed rhizome preparation has high bioavailability, good stability and good disintegration performance.
