SUBSTITUTED N (2 (AMINO) 2 OXOETHYL)BENZAMIDE INHIBITORS OF AUTOTAXIN AND THEIR PREPARATION AND USE IN THE TREATMENT OF LPA DEPENDENT OR LPA MEDIATED DISEASES
RUEBSAM FRANK,WANG CE,NI HAIHONG,MULVIHILL MARK J,BABISS LEE,RENZETTI LOUIS,ZHANG YING
申请号:
IN201617039929
公开号:
IN201617039929A
申请日:
2016.11.23
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts synthesis intermediates formulations and methods of disease treatment therewith including cancer lymphocyte homing chronic inflammation neuropathic pain fibrotic diseases thrombosis and cholestatic pruritus mediated at least in part by ATX.