ASH1L inhibitors and methods of treatment therewith

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专利权人:

The Regents of the University of Michigan

发明人:

Grembecka, Jolanta,Cierpicki, Tomasz,Rogawski, David,Borkin, Dmitry,Klossowski, Szymon,Zhuang, Jin,Montgomery, Deanna,Deng, Jing,Szewczyk, Marta,Li, Hao

申请号：

AU2017263574

公开号：

AU2017263574A1

申请日:

2017.05.12

申请国别(地区):

AU

年份:

2018

代理人:

摘要：

Provided herein are small molecule inhibitors of ASH1L activity and small molecules that facilitate ASH1L degradation and methods of use thereof for the treatment of disease, including acute leukemia, solid cancers and other diseases dependent on activity of ASH1L.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/