SUBSTITUTED N-(2-(AMINO)-2OXOETHYL)BENZAMIDE INHIBITORS OF AUTOTAXIN AND THEIR PREPARATION AND USE IN THE TREATMENT OF LPA-DEPENDENT OR LPA-MEDIATED DISEASES
Frank Ruebsam,Ce Wang,Haihong Ni,Mark J. Mulvihill,Lee Babiss,Louis Renzetti,Ying Zhang
申请号：
US15303848
公开号：
US20170037007A1
申请日:
2015.04.21
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present invention relates to compounds according to Formula I and pharmaceutically acceptable salts, synthesis, intermediates, formulations, and methods of disease treatment therewith, including cancer, lymphocyte homing, chronic inflammation, neuropathic pain, fibrotic diseases, thrombosis, and cholestatic pruritus, mediated at least in part by ATX.
