THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM
发明人:
OLSON, ERIC,VAN ROOIJ, EVA
申请号：
CA2705325
公开号：
CA2705325C
申请日:
2008.11.10
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
A family of microRNAs, called the miR-15 family, which includes miR-195, areshown to be up-regulated duringpathological cardiac remodeling and repress the expression of mRNAs requiredfor cell proliferation and survival, with consequentloss of cardiomyocytes. Strategies to block expression of the miR-15 family inthe heart as a treatment for diverse cardiac diseaseare provided.
