Micro-RNAs of the miR-15 family modulate cardiomyocyte survival and cardiac repair

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专利权人:

The University of Texas System;Board of Regents

发明人:

Van Rooij, Eva,Olson, Eric

申请号：

AU2008323652

公开号：

AU2008323652B2

申请日:

2008.11.10

申请国别(地区):

AU

年份:

2014

代理人:

摘要：

A family of microRNAs, called the miR-15 family, which includes miR-195, are shown to be up-regulated during pathological cardiac remodeling and repress the expression of mRNAs required for cell proliferation and survival, with consequent loss of cardiomyocytes. Strategies to block expression of the miR-15 family in the heart as a treatment for diverse cardiac disease are provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/