Method of regulating proliferation and differentiation of keratinocyes

• 收藏
• 分享

专利权人:

Eli Sprecher;Janna Nousbeck

发明人:

Eli Sprecher,Janna Nousbeck

申请号：

US13127058

公开号：

US08912142B2

申请日:

2010.02.28

申请国别(地区):

US

年份:

2014

代理人:

摘要：

Provided are methods of regulating keratinocytes proliferation and differentiation by subjecting keratinocytes to an agent capable of modulating activity or expression of IGFBP7, thereby regulating keratinocytes proliferation and differentiation. Also provided are methods of treating pathologies characterized by hyperproliferative keratinocytes by administering IGFBP7 polypeptide or a polynucleotide encoding IGFBP7 polypeptide to a subject.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/