FIELD: medicine. ^ SUBSTANCE: group of inventions relates to medical technology, in particular to method and device for control of state of patient's autonomous nervous system under anesthesia. Method is realised by device which includes measuring equipment for registration of signal of skin conductivity and control unit. In accordance with the method during interval of measurements signal of skin conductivity is registered, points of local minimums are identified, integration intervals are selected, function of linear inclination, as well as integral are calculated from difference of values of skin conductivity signal and linear inclination function in case, when signal of skin conductivity is higher than values of function of linear inclination, first index of state of patient's autonomous nervous system under anesthesia is calculated. Also, selected is subset of measurement interval values with beginning in the first point of minimum, value of skin conductivity is selected in said point as constant value,