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Compositions and methods for improved efficacy of penicillin-type antibiotics
专利权人:
Henry H. Flanner
发明人:
Henry H. Flanner,Robert J. Guttendorf,Susan P. Clausen,Donald Treacy,Beth A. Burnside
申请号:
US11636291
公开号:
US08357394B2
申请日:
2006.12.08
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Disclosed are once-a-day penicillin-type antibiotic products comprising at least one modified release dosage form comprising penicillin-type antibiotics and pharmaceutically acceptable carriers, which compositions provide T>MIC90 in the serum for at least 5 hours (preferably for at least five consecutive hours), within a 24-hour dosing interval, for a given bacterial pathogens MIC90, while providing a total dosage of the penicillin-type antibiotic for a 24-hour dosing interval.
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