PROCESS FOR THE PREPARATION OF FREEZE-DRIED 2-[(3-AMINOPROPYL)AMINO]ETHANETHIOL FORMULATION

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专利权人:

CLEVEXEL PHARMA;INSTITUT GUSTAVE ROUSSY

发明人:

Xiuping WANG-ZHANG,Perrine PIVETTE,Karine GONZALEZ,Eric DEUTSCH,Céline CLEMENSON

申请号：

US16465505

公开号：

US20200239414A1

申请日:

2017.11.29

申请国别(地区):

US

年份:

2020

代理人:

摘要：

A process for the preparation of freeze-dried 2-[(3-aminopropyl)amino]ethanethiol including the following steps: a) the reaction of a solution of amifostine with a strong acid, to obtain a solution of 2-[(3-aminopropyl)amino]ethanethiol, and b) the freeze-drying of the solution of 2-[(3-aminopropyl)amino]ethanethiol, with or without addition of excipients.

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