Qian-sheng Yu;William D. Figg;Nigel H. Greig;Harold Holloway;Tony Giordano
发明人:
Nigel H. Greig,Harold Holloway,Arnold Brossi,Xiaoxiang Zhu,Tony Giordano,Qian-sheng Yu,William D. Figg
申请号:
US13648625
公开号:
US08853253B2
申请日:
2012.10.10
申请国别(地区):
US
年份:
2014
代理人:
摘要:
Thalidomide analogs that modulate tumor necrosis factor alpha (TNFα) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.