Nigel H. Greig,Harold Holloway,Arnold Brossi,Xiaoxiang Zhu,Tony Giordano,Qian-sheng Yu,William D. Figg
申请号:
US13153355
公开号:
US08546430B2
申请日:
2011.06.03
申请国别(地区):
US
年份:
2013
代理人:
摘要:
Thalidomide analogs that modulate tumor necrosis factor alpha (TNF-α) activity and angiogenesis are disclosed. In particularly disclosed embodiments, the thalidomide analogs are isosteric sulfur-containing analogs. Also disclosed are methods of treating a subject with the analogs.