LI, CHAN-JUNG,CHOU, DAVID CHIH-KUANG,HUANG, JIN-DING,TSAI, SHIN, JR.,KUO, SHU-WEN,TIEN, YU-EN
申请号：
CA2987378
公开号：
CA2987378A1
申请日:
2016.05.27
申请国别(地区):
CA
年份:
2016
代理人:
摘要：
The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a solution comprising a pharmaceutically acceptable oil and an oil-miscible retaining solvent, as well as manufacturing processes and medical uses of the formulations. The invention further provides methods for adjusting the duration of action of the formulations by varying the ratio of the pharmaceutically acceptable oil and the oil-miscible retaining solvent.
