Li, Chan-Jung,Chou, david chih-Kuang,Huang, Jin-Ding,Tsai Jr., Shin,Kuo, Shu-Wen,Tien, Yu-En
申请号:
AU2016269337
公开号:
AU2016269337A1
申请日:
2016.05.27
申请国别(地区):
AU
年份:
2018
代理人:
摘要:
The present invention relates to injectable, extended-release, pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a solution comprising a pharmaceutically acceptable oil and an oil-miscible retaining solvent, as well as manufacturing processes and medical uses of the formulations. The invention further provides methods for adjusting the duration of action of the formulations by varying the ratio of the pharmaceutically acceptable oil and the oil-miscible retaining solvent.