LI CHAN JUNG,CHOU DAVID CHIH KUANG,HUANG JIN DING,TSAI SHIN JR,KUO SHU WEN,TIEN YU EN
申请号:
IN201727046908
公开号:
IN201727046908A
申请日:
2017.12.27
申请国别(地区):
IN
年份:
2018
代理人:
摘要:
The present invention relates to injectable extended release pharmaceutical formulations comprising a nalbuphine ester prodrug homogenously dissolved in a solution comprising a pharmaceutically acceptable oil and an oil miscible retaining solvent as well as manufacturing processes and medical uses of the formulations. The invention further provides methods for adjusting the duration of action of the formulations by varying the ratio of the pharmaceutically acceptable oil and the oil miscible retaining solvent.