A method and composition for lipid therapy by administering to thesubject an effective amount of a dyslipidemic agent and omega-3 fatty acids.The method may be for the treatment of patients with hypertriglyceridemia,hypercholesterolemia, mixed dyslipidemia, coronary heart disease (CHD),vascular disease, artherosclerotic disease and related conditions, and theprevention or reduction of cardiovascular and vascular events.