Jonathan Wall;José W. Saldanha;Peter A. Seubert;Dale B. SCHENK
发明人:
Dale B. SCHENK,Peter A. Seubert,Jonathan Wall,José W. Saldanha
申请号：
US13460622
公开号：
US20120321555A1
申请日:
2012.04.30
申请国别(地区):
US
年份:
2012
代理人:
摘要：
Methods useful for effecting prophylaxis or treatment of amyloidosis, including AA Amyloidosis and AL amyloidosis, by administering peptides comprising neoepitopes, such as AA fragments from a C-terminal region of AA, and antibodies specific for neoepitopes of aggregated amyloid proteins, for example, antibodies specific for the C-terminal region of AA fibrils. Antibodies for inhibition of formation and/or increasing clearance of amyloid deposits in a patient thus effecting prophylaxis or treating amyloid disease.
