An ultrasound observation apparatus includes: an ultrasound probe a transmitting-receiving section an image processing section an input section a reference image storage section a first position correction section a movie storage section a TIC analysis section a second position correction section a sensor and a positional information storage section, wherein the first position correction section automatically corrects, based on information of a position and direction of the ultrasound probe, a scanning plane to allow a reference image to be constantly displayed, the second position correction section automatically corrects a position of second region of interest, based on the information of the position and direction of the ultrasound probe, and the transmitting-receiving section controls an output of ultrasound beam to allow an output of ultrasound beam in acquisition of temporal variation data of contrast luminance to be larger than an output of ultrasound beam in acquisition of volume data.
