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METHOD FOR TREATMENT OR PREVENTION OF BACTERIAL VAGINOSIS
专利权人:
СТАРФАРМА ПТИ ЛТД (AU)
发明人:
ПОЛЛ Джереми Роберт Артур (AU),ФЭРЛИ Джасинт Кинкейд (AU),ПРАЙС Клэр Фрэнсис (AU),ЛЬЮИС Гарет Рис (AU)
申请号:
RU2013155620/15
公开号:
RU2013155620A
申请日:
2011.07.14
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A method of treating or preventing bacterial vaginosis in a subject, wherein said method comprises administering to the subject an effective amount of a macromolecule containing a dendrimer based on polylysine, polyamidoamine, poly (hydroxylamine ester) or poly (propyleneimine) 1-5 generations and one or more sulfonic acid functional groups attached to one or more surface amino groups of an external dendrimer generation, wherein said effective amount is from 40 mg to 100 mg of a macromolecule per day. 2. The method of claim 1, wherein the effective amount is from 40 mg to 60 mg of the macromolecule per day. A method according to claim 1 or 2, wherein the effective amount is administered as a single dose. The method of claim 1, wherein the administration is vaginal administration. The method of claim 1, wherein the macromolecule is administered in a gel composition. A method for alleviating or preventing one or more symptoms and / or one or more diagnostic criteria for bacterial vaginosis in a subject, the method comprising administering to the subject an effective amount of a macromolecule containing a dendrimer based on polylysine, polyamidoamine, poly (hydroxylamine ester) or poly (propyleneimine) 1 -5 generations and one or more sulfonic acid-containing functional groups attached to one or more surface amino groups of an external dendrimer generation, where one or more sym volumes and / or diagnostic criteria are selected from: i) Nugent scores, ii) key cells, iii) odor tests, iv) vaginal discharge, v) vaginal pH, and vi) unpleasant odor. 7. The method according to claim 6, where the effective amount is from 40 mg to 100 mg macromolecule1. Способ лечения или профилактики бактериального вагиноза у субъекта, где указанный способ включает введение субъекту эффективного количества макромолекулы, содержащей дендример на основе полилизина, полиамидоамина, поли(эфира гидроксиламина) или поли(пропиленимина) 1-5 генераций и одну или более содержащих сульфоновую кислоту
来源网站:
中国工程科技知识中心
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