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METHODS FOR TREATING INTESTINAL DISEASES
专利权人:
ЛТД. (US);САЛИКС ФАРМАСЬЮТИКАЛЗ
发明人:
ФОРБЗ Уилльям (US),ДЖОНСОН Лорин (US)
申请号:
RU2014104362/15
公开号:
RU2014104362A
申请日:
2014.02.07
申请国别(地区):
RU
年份:
2015
代理人:
摘要:
1. A method of treating intestinal diseases (ZK) with a stable response to an antibiotic, comprising administering a therapeutically effective amount of a rifamycin class antibiotic to a patient in need thereof, selecting a patient to respond to the treatment after treatment for from about 1 to about 24 weeks; and withdrawal of treatment from the patient responding to treatment, where after withdrawal of treatment there is a steady response. The method of claim 1, wherein the intestinal diseases include irritable bowel syndrome associated with diarrhea (dBCS). The method of claim 1, wherein the bowel disease comprises hepatic encephalopathy. The method of claim 3, wherein rifaximin is administered to a patient with hepatic encephalopathy from about 28 days to about 24 months. The method according to claim 1, wherein the resistance of the response includes continuous adequate relief of symptoms after discontinuation of treatment. The method of claim 1, wherein at least 50% respond to the treatment. The method of claim 1, wherein the therapeutically effective amount comprises from about 50 mg to about 6000 mg. The method of claim 1, wherein the therapeutically effective amount is from about 100 mg to about 2500 mg two times a day. The method of claim 1, wherein the therapeutically effective amount is from about 50 mg to about 2000 mg three times a day. The method of claim 1, wherein the therapeutically effective amount is 550 mg three times a day. The method of claim 1, wherein the therapeutically effective amount is 550 mg twice daily. The method of claim 1, wherein the therapeutically effective amount is 600 mg / day. The method of claim 1, wherein therapeutically effective1. Способ лечения заболеваний кишечника (ЗК) с устойчивым ответом на антибиотик, включающий введение терапевтически эффективного количества антибиотика класса рифамицина пациенту, нуждающемуся в этом,выбор пациента, который отвечает на лечение, после проведения лечения в течение от приблизительно
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