The present invention provides methods of reducing the vircidal activity of a composition comprising a PCV-2 antigen as well as antigenic preparations and immunogenic compositions comprising a PCV-2 antigen, wherein the viricidal activity has been reduced. In addition, the present invention also relates to a method of increasing the immunogenicity of an immunogenic composition comprising a PCV-2 antigen as well as immunogenic composition with an increased immunogenicity.本發明提供降低包含PCV-2抗原之組合物之殺病毒活性的方法,以及包含PCV-2抗原之抗原性製劑及免疫原性組合物,其殺病毒活性已降低。此外,本發明亦關於一種提高包含PCV-2抗原之免疫原性組合物之免疫原性的方法,以及具有提高免疫原性之免疫原性組合物。(無元件符號說明)
