A pre-shift set of fiducials each including a pre-shift fiducial impedance location and a pre-shift fiducial magnetic location can be determined. The pre-shift fiducial impedance locations and the pre-shift fiducial magnetic location are associated with a medical device. A post-shift set of fiducials each including a post-shift fiducial impedance location and a post-shift fiducial magnetic location can be determined. The post-shift fiducial impedance locations and the post-shift fiducial magnetic locations are associated with the medical device. A pre-shift transformation can be fit to the pre-shift set of fiducials and a post-shift transformation can be fit to the post-shift set of fiducials. A determination can be made whether the pre-shift transformation differs from the post-shift transformation. An indication that an impedance shift has occurred between the pre-shift set of fiducials and the post-shift set of fiducials can be generated based on the difference between the pre-shift transformation and the post-shift transformation.