Banci, Lucia,Cantini, Francesca,Dragonetti, Sara,Gentile, Maria Antonietta,Veggi, Daniele,Scarselli, Maria,Pizza, Mariagrazia
申请号：
AU2010310985
公开号：
AU2010310985A1
申请日:
2010.10.27
申请国别(地区):
AU
年份:
2012
代理人:
摘要：
The factor H binding activity of meningococcal fHBP can be uncoupled from its bactericidal sensitivity. NMR studies have identified various amino acid residues involved in the fHBP/fH interaction and one or more of these residues is modified in a fHBP to reduce or eliminate its ability to bind to fH.
