MODIFIED MENINGOCOCCAL FHBP POLYPEPTIDES

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专利权人:

发明人:

申请号：

EP10782038.3

公开号：

EP2493499A1

申请日:

2010.10.27

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

The factor H binding activity of meningococcal fHBP can be uncoupled from its bactericidal sensitivity. NMR studies have identified various amino acid residues involved in the fHBP/fH interaction and one or more of these residues is modified in a fHBP to reduce or eliminate its ability to bind to fH.

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中国工程科技知识中心

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