MATERIJALI I POSTUPCI ZA MODULACIJU ZARASTANJA TETIVA

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专利权人:

THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW

发明人:

GILCHRIST, DEREK, STEWART,MILLAR, NEAL, LINDSAY

申请号：

RSP20180202

公开号：

RS56915B1

申请日:

2015.01.14

申请国别(地区):

RS

年份:

2018

代理人:

摘要：

The invention relates to the use of microRNA 29 and precursors and mimics thereof for the modulation of tendon injury and the biomechanical properties of tendon. In particular, the invention derives from the finding that synthesis of type 1 collagen in tenocytes is less sensitive to miR-29 than is synthesis of type 3 collagen, thus enabling the balance between the collagen subtypes to be modulated in favor of type 1 collagen, mitigating reduction in biomechanical properties during healing.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/