AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F. S.P.A.
发明人:
ALISI, MARIA ALESSANDRA,CAZZOLLA, NICOLA,DRAGONE, PATRIZIA,FURLOTTI, GUIDO,MAUGERI, CATERINA,OMBRATO, ROSELLA,MANCINI, FRANCESCA
申请号:
CA2860250
公开号:
CA2860250A1
申请日:
2013.02.07
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
The present invention relates to the 1 H-indazole-3-carboxamide compounds having the following general formula (I) as glycogen synthase kinase 3 beta (GSK-3ß) inhibitors and to their use in the treatment of GSK-3p-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; (viii) epilepsies; and (ix) neuropathic pain.