AZIENDE CHIMICHE RIUNITE ANGELINI FRANCESCO A.C.R.A.F.S.P.A.
发明人:
ALISI, MARIA ALESSANDRA,CAZZOLLA, NICOLA,GAROFALO, BARBARA,FURLOTTI, GUIDO,MAGARO', GABRIELE,OMBRATO, ROSELLA,MANCINI, FRANCESCA
申请号:
CA2860466
公开号:
CA2860466A1
申请日:
2013.02.08
申请国别(地区):
CA
年份:
2013
代理人:
摘要:
1 H-indazole-3-carboxamide compounds as glycogen synthase kinase 3 beta inhibitors. The present invention relates to the 1 H-indazole-3-carboxamide compounds for use as glycogen synthase kinase 3 beta (GSK-33) inhibitors and to their use in the treatment of GSK-3p-related disorders such as, for example, (i) insulin-resistance disorders; (ii) neurodegenerative diseases; (iii) mood disorders; (iv) schizophrenic disorders; (v) cancerous disorders; (vi) inflammation, (vii) substance abuse disorders; and (viii) epilepsies.