COMPOSITIONS AND METHODS FOR PREVENTION OF ESCAPE MUTATION IN THE TREATMENT OF HER2/NEU OVER EXPRESSING TUMORS

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专利权人:

发明人:

SHAHABI VAFA

申请号：

IN1139/DELNP/2014

公开号：

IN2014DN01139A

申请日:

2014.02.15

申请国别(地区):

IN

年份:

2016

代理人:

摘要：

This invention provides compositions and methods for treating and vaccinating and inducing an immune response against a Her2/neu antigen expressing tumor in a non human animal. An exemplary method of treating a Her 2/neu expressing tumor growth or cancer in a non human animal the method comprising the step of administering a recombinant Listeria comprising nucleic acid molecule encoding a fusion polypeptide wherein said fusion polypeptide comprises a Her2/neu chimeric antigen fused to an additional adjuvant polypeptide is provided.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/